The Prince of Wales is an avid football fan and is often seen supporting Aston Villa.
In his message, he thanked everyone on and off the field for a memorable tournament.
The Royal Family also reacted to England’s defeat.
A post on their social media offered commiserations to Harry and the team, alongside a photo of captain Harry Kane solemnly embracing Jude Bellingham.
It added that while the Three Lions may be hurting today, they remain the nation’s pride and will rise again.
Sir Keir’s final address to the House of Commons as prime minister on Wednesday also included several nods to the side’s tense build-up to the knockout match.
After full-time, Sir Keir said the result wasn’t what the country hoped for, but praised the England team for giving their all.