Gian Piero Gasperini is encountering difficulties in midfield for the upcoming match against Sassuolo.
In addition to Neil El Aynaoui, who is currently participating in the Africa Cup of Nations, Roma will also be missing Bryan Cristante this Saturday night.
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The Giallorossi midfielder received a yellow card during the match against Lecce.
In the 84th minute, referee Juan Luca Sacchi cautioned him for an on-field incident, resulting in his suspension.
As a result, Gasperini will have to do without Cristante in the clash with Sassuolo.
With both Cristante and El Aynaoui unavailable, the only midfielders left eligible for selection are Manu Koné and Niccolò Pisilli, who are expected to start on Saturday evening.
This presents a considerable challenge for the Giallorossi coach, who is once again facing a depleted lineup at the Olimpico due to international commitments and player absences.
On a positive note, Mario Hermoso and Gianluca Mancini will be back in contention.